Each year shorebirds use habitats across a vast geography, undertaking some of the longest migrations of any animals on earth. Atlantic Flyway shorebirds are exposed to a diverse set of human-induced threats like habitat loss and change, hunting in the Caribbean, and predators. Effective shorebird conservation thus requires a wide-ranging approach to identify and reduce these threats at sites all along the flyway. Only with such a flyway-scale approach can we reverse the serious declines we are witnessing in many of our shorebird populations.